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Course on Molecular Evolution, Phylogenetics and Adaptation

National and International Bioinformatics Courses (master and/or PhD programmes) select one of the alternative formats to obtain the main concepts and the basic skills in molecular evolution and phylogenetics. The course consists in a serie of lectures and PC lab excercises.

 

Topics

Systematics Schools, Molecular Evolution, Homology, Neutral Theory, Rates of Evolution, Molecular clock, Species vs Gene trees, Rooted vs unrooted trees, Dendogram, Cladogram and Phylogram, Monophyletic, Paraphyletic and Polyphyletic Groups, Models of Molecular Evolution, Distance Based Methods, Maximum Parsimony, Maximum Likelihood, Bayesian Methods, Statistical Tests on Evolutionary Models and Topologies, Molecular Adaptation, Applications.

Excercises with: PHYLIP, MEGA, PhyML, MrBayes, ModelTest, ProtTest, PAML, CodeML, SLR, and...

Phylemon Web  Server

 

Chose format

5 days, 149 pp.

3 days, 83pp.

1 day, 66 pp.

Adaptive Evolution

PC Lab Hands On

Links to our courses

 

Major References

  • Swofford, D. L., G. J. Olsen, P. J. Waddell, and D. M. Hillis. Phylogenetic inference. In D. M. Hillis, C. Moritz, and B. K. Mable, editors, Molecular Systematics. (2nd ed.), Sinauer Associates, Inc., Sunderland Massachusetts,1996.

  • Li, W.S. Molecular Evolution. Sinauer Associates, Inc., Sunderland, MA, 1997.

  • Page, R. D. M. & E. C. Holmes. Molecular Evolution. A phylogenetic approach. Blackwell, Oxford, 1998.

  • Nei, M. and S. Kumar. Molecular Evolution and Phylogenetics. Blackwell Science Ltd., Oxford, London, 1998.

  • Salemi,M. and A. M. Vandamme (ed). The Phylogenetic Handbook. Cambridge Univ. Press, UK, 2003.

  • Felsenstein, J. Inferring Phylogenies. Sinauer associates, Inc., Sunderland, MA, 2004.

  • Balding, Bishop and Cannings. Handbook of Statistical Genetics. Wiley. 2005.

  • R. Nielsen. Statistical Methods in Molecular Evolution. Springer. 2005.

  • Z. Yang. Computational Molecular Evolution. OSEE. Oxford Univ. Press. 2006.